The present work is about the synthesis of hybrid material organic-inorganic for drug delivery system. Particularly it was investigated Resveratrol as active molecule for its interesting properties like anti-oxidant, cardioprotective, anti-aging and neuro-protective. All the samples obtained were characterized by means of FT-IR analysis, TG/DTG measurement and XRD diffraction. After the optimization of the synthesis the samples were analyzed by UV technique in order to verify the conservation of Resveratrol inside the clay in its active form.
Il presente lavoro di tesi riguarda la preparazione di sistemi argilla-principio attivo per il rilascio controllato di farmaci. In particolare, si è preso in considerazione i sistemi argilla-Resveratrolo, viste le particolari proprietà del Resveratrolo quali antiossidanti, cardio-protettive, anti-aging e neuro-protettive. Tutti i sistemi preparati sono stati caratterizzati mediante analisi FT-IR, TG, DTG e XRD. Dopo l'ottimizzazione della tecnica di preparazione sono state effettuate analisi UV al fine di verificare la corretta conservazione del resveratrolo nella sua forma attiva.
Sistemi ibridi organici-inorganici per il rilascio controllato di resveratrolo : preparazione e caratterizzazione
ARRIGHI, ELEONORA
2014/2015
Abstract
The present work is about the synthesis of hybrid material organic-inorganic for drug delivery system. Particularly it was investigated Resveratrol as active molecule for its interesting properties like anti-oxidant, cardioprotective, anti-aging and neuro-protective. All the samples obtained were characterized by means of FT-IR analysis, TG/DTG measurement and XRD diffraction. After the optimization of the synthesis the samples were analyzed by UV technique in order to verify the conservation of Resveratrol inside the clay in its active form.File | Dimensione | Formato | |
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https://hdl.handle.net/10589/112583