Global respiratory motion model based on 4D CT and 2D cine-MRI

The developed project tackled the issue of respiratory motion in developing techniques to acquire images or guide interventions in abdominal and thoracic organs. Motion models offer a possible solution to these problems, and as a result the field of respiratory motion modelling has become very active over the past 15 years. In addition, novel image-guided technologies based on MRI-linac systems can provide an accurate in-room description of motion, thanks to the properties of dynamic MRI acquisitions. However, the transfer of the treatment plan to the treatment delivery phase is still an issue, especially for MRI-guided treatments. The project entailed the comparison of different motion models on phantom and clinical data. Specific goals have been the verification of motion model performance in terms of geometric accuracy and dosimetric results.