Design, synthesis and optimization of a biomimetic thermo responsible hydrogel for chondrocyte encapsulation in a newly devised mid-throughput cartilage-on-chip platform

A multi-chamber microfluidic device was developed for the study of post-traumatic osteoarthritis. In parallel, a new biomimetic and thermosensitive hydrogel was synthesized for encapsulation and subsequent seeding of chondrocytes within the device itself.

E' stato sviluppato un dispositivo microfluidico multi camera per lo studio dell' osteoartrite post-traumatica. In parallelo è stato sintetizzato un nuovo idrogelo biomimetico e termosensibile per l'incapsulazione e la successiva semina di condrociti all'interno del dispostivo stesso.