The pharmaceutical industry is subjected to strict regulations and inspections for which production activities require time and compilation of many documents. This also applies to final packaging activities. For this reason, it is necessary to lighten production processes, especially in the case of a company that has recently left the Big Pharma world and is not very automated. The objective of this study is to optimize packaging flows through Lean Manufacturing techniques. Specifically, reduce packaging times and create a performance monitoring system. To achieve these objectives, an OEE system is created, followed by the use of the SMED technique, with which the analysis and standardization of activities are carried out to increase the availability factor through the parallelization of the activities of operators and mechanics. This is sustained by the introduction of improvements regarding the organization of the department, in particular, for the management of operators, mechanics, documentation, and communication between departments. The results achieved are visible above all thanks to the use of the A3 logic flow and the adoption of Poka Yoke and Kaizen techniques to make the activities simple and free of uncertainties, increasing the availability of the lines and the visibility of information and therefore reducing the possibility of making mistakes. In conclusion, it can be said that better information management and standardization of activities leads to awareness of the role of the operator on the line and greater attention to the execution of the activities as well as to the reduction of the execution time of the same. In addition, the use of OEE allows understanding of where to intervene and which factor to develop the most.
Il settore farmaceutico è sottoposto a norme e rigide ispezioni per cui le attività di produzione richiedono tempo e compilazione di molti documenti. Questo riguarda anche le attività finali di confezionamento. Per questo motivo è necessario snellire i processi di produzione, soprattutto nel caso di un’azienda da poco uscita dal mondo Big Pharma e poco automatizzata. L’obiettivo di questo studio è quello di ottimizzare i flussi di confezionamento attraverso le tecniche della Lean Manufacturing. Nello specifico ridurre i tempi di confezionamento e creare un sistema di monitoraggio delle performance. Per raggiungere questi obiettivi viene creato un sistema OEE, seguita dall’uso della tecnica SMED, con la quale si procede all’analisi e alla standardizzazione delle attività per aumentare il fattore disponibilità attraverso la parallelizzazione delle attività di operatori e meccanici. Il tutto accompagnato dall’introduzione di migliorie riguardo organizzazione del reparto, in particolare per gestione di operatori, meccanici, documentazione e comunicazione tra reparti. I risultati raggiunti sono visibili soprattutto grazie all’uso del flusso logico A3 e l’adozione di tecniche Poka Yoke e Kaizen per rendere le attività semplici e prive di incertezze, aumentando la disponibilità delle linee e la visibilità di informazioni e quindi riducendo la possibilità di commettere errori. In conclusione, si può affermare che una migliore gestione delle informazioni e la standardizzazione di attività porta alla consapevolezza del ruolo dell’operatore sulla linea e una maggiore attenzione sull’esecuzione delle attività nonché alla riduzione del tempo di esecuzione delle stesse. Inoltre, l’uso dell’OEE permette di capire dove intervenire e quale fattore sviluppare maggiormente.
Productivity's improvement in packaging lines of a pharmaceutical company
CENCI, GIULIA
2020/2021
Abstract
The pharmaceutical industry is subjected to strict regulations and inspections for which production activities require time and compilation of many documents. This also applies to final packaging activities. For this reason, it is necessary to lighten production processes, especially in the case of a company that has recently left the Big Pharma world and is not very automated. The objective of this study is to optimize packaging flows through Lean Manufacturing techniques. Specifically, reduce packaging times and create a performance monitoring system. To achieve these objectives, an OEE system is created, followed by the use of the SMED technique, with which the analysis and standardization of activities are carried out to increase the availability factor through the parallelization of the activities of operators and mechanics. This is sustained by the introduction of improvements regarding the organization of the department, in particular, for the management of operators, mechanics, documentation, and communication between departments. The results achieved are visible above all thanks to the use of the A3 logic flow and the adoption of Poka Yoke and Kaizen techniques to make the activities simple and free of uncertainties, increasing the availability of the lines and the visibility of information and therefore reducing the possibility of making mistakes. In conclusion, it can be said that better information management and standardization of activities leads to awareness of the role of the operator on the line and greater attention to the execution of the activities as well as to the reduction of the execution time of the same. In addition, the use of OEE allows understanding of where to intervene and which factor to develop the most.| File | Dimensione | Formato | |
|---|---|---|---|
|
2021_12_Cenci.pdf
accessibile in internet per tutti
Descrizione: Testo della tesi
Dimensione
1.52 MB
Formato
Adobe PDF
|
1.52 MB | Adobe PDF | Visualizza/Apri |
I documenti in POLITesi sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
https://hdl.handle.net/10589/182414